The Melbourne Fire Department responded to a fire at a single-family house on 719 Espanola Way about 8 a.m. Thursday.
The fire caused about $50,000 worth of damage to the house, according to initial estimates.
Firefighters entered the structure to find the kitchen and a couch on fire.
Several snakes and two lizards were rescued from the house while a cat perished in the fire.
No one was home at the time of the fire and no injuries were reported. Investigators are trying to determine the cause of the fire.
Officers from the Brevard County Animal Services and Enforcement were called to assist the reptiles.